Enrofloxacin injection

ʻO Pharmacodynamic Enrofloxacin kahi lāʻau bactericidal ākea ākea i hoʻohana kūikawā ʻia no nā holoholona fluoroquinolone.No ka e.coli, salmonella, klebsiella, brucella, pasteurella, pleuropneumonia actinobacillus, erysipelas, bacillus proteus, pālolo ʻo Mr Charest's bacteria, suppurative corynebacterium, lanakila i ka bacteria pott blood, staphylococcus aureus, mycoplasma, chlamydia, etc. a ʻo ka streptococcus he nāwaliwali, nāwaliwali ka hopena i ka maʻi bacteria anaerobic.Loaʻa iā ia ka hopena post-antibacterial ma luna o nā maʻi bacteria koʻikoʻi.ʻO ke ʻano hana antibacterial o kēia huahana ka mea e pale ai i ka huli ʻana o ka DNA bacteria, e hoʻopilikia i ka replication, transcription a me ka hoʻoponopono hou ʻana o ka DNA bacterial recombination, ʻaʻole hiki i ka bacteria ke ulu a hoʻohua maʻamau a make.

Pharmacokinetics Ua hoʻopili koke ʻia ka lāʻau lapaʻau e ka intramuscular injection.ʻO ka bioavailability he 91.9% i nā puaʻa a me 82% i nā bipi.Hoʻolaha nui ʻia i nā holoholona a hiki ke komo maikaʻi i nā ʻiʻo a me nā wai kino.Ma waho aʻe o ka wai cerebrospinal, ʻoi aku ka kiʻekiʻe o ka neʻe ʻana o nā lāʻau i loko o nā kiko āpau ma mua o ka plasma.ʻO ka metabolism hepatic nui ka wehe ʻana i ka ethyl o ke apo 7-piperazine e hana i ka ciprofloxacin, a ukali ʻia e ka oxidation a me ka glucuronic acid binding.ʻO ka mea nui ma o ka puʻupaʻa (renal tubular secretion and glomerular filtration) hoʻokuʻu, 15% ~ 50% i ke ʻano kumu mai ka mimi.ʻO ka hoʻopau ʻana i ka hapalua o ke ola o ka injection intramuscular he 5.9 mau hola i nā bipi waiu, 1.5 ~ 4.5 hola i nā hipa, a me 4.6 mau hola i ka puaʻa.